British Journal of Pharmacology Irritable bowel syndrome is a common condition that is challenging to treat, and novel drugs are needed for this condition. Previously, a chronic vicarious social defeat stress mouse model exhibits IBS-like symptoms. Also agonists of the opioid δ-receptor exert anti-stress effects in rodents with minimal adverse effects. In this study, researchers evaluated the effects of δ-receptor agonists on the IBS-like symptoms in cVSDS mice.
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Therapeutic Advances in Gastroenterology via SageJournals Endoscopic submucosal dissection is the first-line treatment for gastric mucosal lesions. The artificial ulcers caused by ESD can lead to bleeding, perforation and other adverse events. This study aimed to evaluate the efficacy of alternate mucosa-submucosa clip in preventing adverse events following ESD for gastric mucosal lesions.
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The Lancet Since the first, seminal randomised controlled trial in inflammatory bowel disease in 1955, the central tenets for high-quality clinical trials have been recognised as robust and appropriate design, conduct, analysis and reporting. The research question to be answered affects all these areas. However, recent data have shown that the primary research question in an RCT is often poorly specified and unclear to readers of trial reports. In IBD, this lack of clarity might be, in part, due to the increasing complexity of clinical trials; therefore, increased methodological awareness might assist clinical readers in understanding and interpreting the findings from such trials.
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JGH Open via National Library of Medicine Walled‐off necrosisis a potentially fatal condition best treated endoscopically with metal or plastic stents. This study compares the clinical outcomes of these stents.
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Joint CDDW-CLM Conference 2025 When: February 25 - March 2 Location: Manila Country: Philippines Organizer(s): World Gastroenterology Organisation and the Philippine Society of Gastroenterology Learn More
Train the Trainers Manila When: March 6-8 Location: Manila Country: Philippines Organizer(s): World Gastroenterology Organisation and the Philippine Society of Gastroenterology Learn More
28th Annual Meeting When: March 12-14, 2025 Location: Madrid Country: Spain Organizer(s): Asociación Española de Gastroenterología (AEG) Learn More
APASL 2025 When: March 26-30 Location: China National Convention Center Country: Beijing, China Organizer(s): Asian Pacific Association for the Study of the Liver Learn More