How safe is ustekinumab before, during and after pregnancy in IBD?
Clin Gastroenterol Hepatol
Among patients and some physicians there are many incorrect beliefs regarding the use of biologics during pregnancy; medical counselling is, therefore, extremely important. On the one hand, it is known that active inflammation in IBD is associated with an increased risk of adverse pregnancy outcomes, while on the other, treatments must be safe for both the woman and the fetus. Even though most conventional drugs used in IBD (except for methotrexate) are considered low risk during conception and pregnancy, for newer medications, evidence is still limited.
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Review by Prof. Edyta Tulewicz-Marti (Poland)