ISSUE HIGHLIGHTS

WHAT'S HOT IN THE LITERATURE

How safe is ustekinumab before, during and after pregnancy in IBD?

Clin Gastroenterol Hepatol
Among patients and some physicians there are many incorrect beliefs regarding the use of biologics during pregnancy; medical counselling is, therefore, extremely important. On the one hand, it is known that active inflammation in IBD is associated with an increased risk of adverse pregnancy outcomes, while on the other, treatments must be safe for both the woman and the fetus. Even though most conventional drugs used in IBD (except for methotrexate) are considered low risk during conception and pregnancy, for newer medications, evidence is still limited.
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Review by Prof. Edyta Tulewicz-Marti (Poland)


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Risk factors for Crohn's disease — get a dog, get rid of the pet bird!

Gastroenterology & Clin Gastroenterol Hepatol
These papers provide a wake-up call for all of us who care for patients with Crohn's disease and urge us to give more attention to the environment in management and even prevention. The findings with regard to family size and living with a dog may initially seem bizarre but on reflection are scarcely surprising given the well-documented description of the protective effects of intense cohabitation and contact with animals against immune-mediated disorders, an effect that may be generated via the microbiome.
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Review by Prof. Eamonn Quigley (USA)



GI NEWS AROUND THE WORLD

IBD patients cited these issues as top barriers to care

MedPage Today
A survey study reveals that patients with inflammatory bowel disease often delay or cannot access medical care or medications due to inadequate appointment availability and insurance difficulties. The study highlights the significant role of social determinants of health in patients' ability to care for themselves and maintain health  Read More

Intravenous to subcutaneous infliximab switch shows promise in IBD management

Medscape
Switching from established intravenous therapy to subcutaneous infliximab was associated with high treatment persistence, stable clinical disease activity and consistent faecal calprotectin levels in patients with inflammatory bowel disease.  Read More

6 things to know about genetics in GI cancers

Gastroenterology & Endoscopy News
As genetic testing is fast becoming a defining aspect of cancer care prevention, treatment and recurrence monitoring, its role is becoming more apparent in gastroenterology. Approximately 10% to 15% of colorectal cancers are clearly hereditary, with mutations in single genes that predispose a person to the development of these cancers.  Read More

Higher calcium intake linked to reduced colorectal cancer risk

MedPage Today
Higher calcium intake was consistently associated with a reduced risk of colorectal cancer across calcium sources and tumor sites, according to a cohort study using data from the NIH-AARP Diet and Health Study. Among over 470,000 participants who were cancer-free at baseline, higher total calcium intake was associated with a lower risk of colorectal cancer.  Read More

EVENTS CALENDAR

Joint CDDW-CLM Conference 2025
When: February 25 - March 2
Location: Manila
Country: Philippines
Organizer(s): World Gastroenterology Organisation and the Philippine Society of Gastroenterology
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Train the Trainers Manila
When: March 6-8
Location: Manila
Country: Philippines
Organizer(s): World Gastroenterology Organisation and the Philippine Society of Gastroenterology
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28th Annual Meeting
When: March 12-14, 2025
Location: Madrid
Country: Spain
Organizer(s): Asociación Española de Gastroenterología (AEG)
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2025 Annual Meeting of the Philippine Society of Gastroenterology
When: March 12-15, 2025
Location: Grand Hyatt
Country: Manila, Philippines
Organizer(s): Philippine Society of Gastroenterology
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Dutch Digestive Disease Days 2025
When: March 19-20
Location: Veldhoven
Country: Netherlands
Organizer(s): NVGE
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HUG 2025
When: March 20-22
Location: Seoul
Country: Korea
Organizer(s): Korean College of Helicobater and Upper Gastrointestinal Research
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The 55th Annual Meeting of GEST
When: March 22-23
Location: Taipei
Country: Taiwan
Organizer(s): The Gastroenterological Society of Taiwan
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APASL 2025
When: March 26-30
Location: China National Convention Center
Country: Beijing, China
Organizer(s): Asian Pacific Association for the Study of the Liver
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ESGE Days 2025
When: April 3-5
Location: Barcelona
Country: Spain
Organizer(s): European Society of Gastrointestinal Endoscopy
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Scrubs and Heels Leadership Summit 2025
When: April 4-6br> Location: Rancho Palos Verdes, Calif.
Country: United States
Organizer(s): AScrubs and Heels
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